| Valtrex (U.S.N.L.M.) | |
|---|---|
| Dosing/ Zoster | 1 gram po tid for 7 days |
| Dosing/ Herpes Simplex | 500 mg orally tid for 7 days |
| Chem Specs | valacyclovir |
| Quantities | 500mg, 1g |
| Cost | 168.00/30 tab/1g (generic) tablets |
| Class | Acyclovir is a guanine analogue antiviral. |
| Action | Valacyclovir is a pro-drug of acyclovir |
| Activity | Valacyclovir is active against Varicella Zoster(VZV), and is about twice as effective against HSV-1 and HSV-2. Valacyclovir is active against Varicella Zoster(VZV), and is about twice as effective against HSV-1 and HSV-2. |
| Usage | Valtrex is indicated for the treatment of herpes zoster (shingles) and is commonly used for HSV-1 and HSV-2. Valtrex is indicated for the treatment of herpes zoster (shingles) and is commonly used for HSV-1 and HSV-2. |
| Initiate therapy at the earliest sign or symptom. | |
| Contraindications | Hypersensitivity to valacyclovir, acyclovir, or their components. |
| Pediatric use | Pre-pubertal safety and effectiveness have not been established. |
| Pregnancy | Limited studies in humans have not demonstrated fetal risk. Animal studies have failed to demonstrate fetal risk Limited studies in humans have not demonstrated fetal risk. Animal studies have failed to demonstrate fetal risk |
| Steroids are indicated for HSV stromal keratitis but must be avoided in the acute phase of active viral replication on the ocular surface as in acute epithelial keratitis. Steroids are indicated for HSV stromal keratitis but must be avoided in the acute phase of active viral replication on the ocular surface as in acute epithelial keratitis. |