| Upneeq® (U.S.N.L.M.) | |
|---|---|
| Dosing | One drop daily |
| Chem Specs | oxymetazoline hydrochloride 0.1% |
| Quantities | Cartons of 30 single-use containers in child-resistant foil pouches |
| Cost | 257.00 |
| Class | Alpha adrenoreceptor agonist |
| Action | As a selective α1 and partial α2 agonist oxymetazoline contracts the smooth (Muller's) muscle of the upper lid. |
| Usage | Indicated for the treatment of acquired blepharoptosis in adults. |
| Cautions | Prior assessment of possible underlying disease such as Horner's, myasthenia gravis, etc. is required. Alpha agonist implications for various cardiovascular conditions and Sjögren’s syndrome must be considered. May increase the risk of narrow-angle glaucoma. |
| Contraindications | None |
| Pediatric use | Safety and effectiveness not been established in patients under 13 years of age. |
| Pregnancy | Teratogenic when fed to rats at 28x (but not at 7x) the normal comparable human ophthalmic dose. |
| Remove contact lenses prior to use; reinsert 15 minutes following administration. |