| Homatropine (U.S.N.L.M.) | |
|---|---|
| Dosing (uveitis/iritis) | 1 or 2 drops 5% up to q3hr or q4hr (bid to qid common practice) 1 drop 2% bid or tid for children |
| Dosing (cycloplegia) | Instill 1 or 2 drops 2%, repeat in 5 to 10 min if nec. |
| Chem Specs | homatropine HBr 2%, 5% |
| Quantities | 5ml |
| Cost | 33.00/5ml |
| Class | anticholinergic |
| Action | Competitive antagonist for the muscarinic acetylcholine receptor. |
| Usage | Indicated for cycloplegic refraction or for pupil dilation in acute inflammatory conditions of the iris and uveal tract. |
| Increased susceptibility in infants, young children, and in children with blond hair, blue eyes, Down's syndrome, spastic paralysis, or brain damage. |
|
| Contraindications | Untreated narrow-angle glaucoma, or untreated anatomically narrow angles, or hypersensitivity to any component of the preparation. |
| Pediatric use | Homatropine should not be used during the first 3 months of life due to a possible association between the cycloplegia produced and the development of amblyopia. |
| Pregnancy | Category C. Animal reproduction studies have not been conducted. |
| Peak mydriasis 40-60 min. Peak cycloplegia 30-60 min. Recovery 1-3 days. Roughly 1/10 as potent as atropine. Nasolacrimal pressure recommended. Isopto Homatropine discontinued by Alcon 2013. Homatropine HBr 5% available from Altaire. |