Augmentin   (U.S.N.L.M.)
Dosing:  (Dacryocystitis,
           Preseptal Cellulitis)
Mild to Moderate: 250mg tid to 500mg bid(q12hr).   Severe: 500mg tid to 875mg bid(q12hr).
Chem Specs amoxicillin / clavulanate (β-lactamase inhibitor)
Quantities Tablets(250, 500, 875mg), Chewable(125, 200, 250, 400mg), Suspension(125, 200, 250, 400mg).
Cost 57.19/20/875mg    generic
Class moderate-spectrum ß-lactam antibiotic / ß-lactamase inhibitor
Action Inhibits cross-linkage between the peptidoglycan polymer chains of bacterial cell
wall. / Inhibits bacterial ß-lactamase enzyme.
Usage Used against ß-lactamase producing strains of H. influenzae, M. catarrhalis, S. aureus,
E. coli, Klebsiella spp as well as ampicillin-susceptible organisms particularly S. pneumoniae.
The q12hr regimen is preferred. 10 day course is typical.
Contraindications Allergy to any of the penicillins. or other ß-lactams. Previous cholestatic
jaundice/hepatic dysfunction associated with Augmentin.
Pediatric use Consult dosing tables and package insert warnings for children under 40kg.
Pregnancy Category B. No animal evidence of teratogenic effects.
    N.L.M. DailyMed page for Augmentin          PDR page for Augmentin