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          Zymar  (U.S.N.L.M.)
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|---|---|---|
| Dosing/ conjunctivitis | 1 drop q2hr x 2days, then qid x 5 days | |
| Dosing/ ulcer | In office loading dose then 2drops q15min for 2-3hr, then qhr, q3-4hr overnight (ung hs less severe cases), qhr day 2, then q2hr to significant resolution, then qid to day 14. |
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| Chem Specs | gatifloxacin 0.3% | |
| Quantities | 5 mL in 10 mL bottle | |
| Cost | 88.00 | |
| Class | fourth-generation fluoroquinolone | |
| Action | Binds bacterial DNA gyrase topoisomerase II and topoisomerase IV | |
| Activity | Active against a very broad range of gram negative and positive organisms. Click heading for details in package insert. |
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| Usage | Indicated for bacterial conjunctivitis, off label for corneal ulcer. | |
| Enhanced gram positive activity with bulky side chains which combat resistance and enhance potency. Good initial kill rate. |
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| Contraindications | Hypersensitivity to Zymar, other quinolones or any components. | |
| Pediatric use | > 1 year | |
| Pregnancy | Category C | |
| BAK preserved. | ||