click here for details           Vigamox  (U.S.N.L.M.)
Dosing/ conjunctivitis 1 drop tid for 7 days
Dosing/ corneal ulcer In office loading dose then 2drops q15min for 2-3hr, then qhr,
q3-4hr overnight (ung hs less severe cases), qhr day 2, then
q2hr to significant resolution, then qid to day 14.
Chem Specs moxifloxacin 0.5%
Quantities 3 ml in 4ml bottle
Cost 111.00
Class fourth-generation fluoroquinolone
Action Binds bacterial DNA gyrase topoisomerase II and topoisomerase IV
Activity Active against a very broad range of gram negative and positive
organisms. Click heading for details in package insert.
Usage Indicated for bacterial conjunctivitis, off label for corneal ulcer.
Enhanced gram positive activity with bulky side chains which combat
resistance and enhance potency. Superior time-kill characteristics.
Better solubility in ophthalmic solution allows higher concentration.
Biphasic molecule may explain enhanced corneal penetration.
Contraindications Hypersensitivity to Moxifloxacin, other quinolones or any components.
Pediatric use > 1 year
Pregnancy Category C
Self preserved.