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           Timoptic  (U.S.N.L.M.)
| |
|---|---|
| Dosing | Initial dose 1 drop 0.25% bid. Reduce to qd dosing if warranted.¹ |
| Chem Specs | timolol maleate 0.25, 0.5% |
| Quantities | 5, 10, 15ml, 0.2 mL unit doses. |
| Cost | 4.00 / 5ml  generic |
| Class | Non-selective beta-adrenergic receptor blocker. |
| Action | Reduces aqueous formation by blocking beta2 receptors on nonpigmented ciliary epithelium. |
| Usage | Indicated in the treatment of elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma. |
| 10 to 20% do not respond adequately to beta-blockers. | |
| Contraindications | Bronchial asthma, a history of bronchial asthma, COPD, sinus bradycardia, second or third degree atrioventricular block, overt cardiac failure, cardiogenic shock or hypersensitivity to any component of the product. |
| Pediatric use | Safety and effectiveness in pediatric patients have not been established. |
| Pregnancy | Category C |
| Available as preservative free 0.2 mL "Ocudose" unit doses, otherwise BAK preserved. |
|
| ¹ 1 drop 0.25% qAM and 1 drop 0.50% qAM for highly pigmented eyes is common practice. |