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           Timoptic  (U.S.N.L.M.)
Dosing Initial dose 1 drop 0.25% bid. Reduce to qd dosing if warranted.¹
Chem Specs timolol maleate 0.25, 0.5%
Quantities 5, 10, 15ml, 0.2 mL unit doses.
Cost 4.00 / 5ml  generic
Class Non-selective beta-adrenergic receptor blocker.
Action Reduces aqueous formation by blocking beta2 receptors on nonpigmented ciliary epithelium.
Usage Indicated in the treatment of elevated intraocular pressure in patients with
ocular hypertension or open-angle glaucoma.
10 to 20% do not respond adequately to beta-blockers.
Contraindications Bronchial asthma, a history of bronchial asthma, COPD, sinus bradycardia,
second or third degree atrioventricular block, overt cardiac failure, cardiogenic
shock or hypersensitivity to any component of the product.
Pediatric use Safety and effectiveness in pediatric patients have not been established.
Pregnancy Category C
Available as preservative free 0.2 mL "Ocudose" unit doses,
otherwise BAK preserved.
¹ 1 drop 0.25% qAM and 1 drop 0.50% qAM for highly pigmented eyes is common practice.