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Polysporin
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| Dosing/ | Apply every 3 or 4 hours for 7 to 10 days | |
| Chem Specs | bacitracin zinc 500 units, polymyxin B sulfate 10,000 units | |
| Quantities | 3.5 gm tube | |
| Cost | 15.00 | |
| Class | Polypeptide antibiotic | |
| Action | Bacitracin interferes with cell wall synthesis. Polymyxin B increases permeability of bacterial cell membrane |
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| Activity | Active against Staphylococcus aureus, streptococci including Streptococcus pneumoniae, Haemophilus influenzae, Neisseria species, and Pseudomonas aeruginosa. |
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| Usage | Indicated for superficial conjunctivitis, keratitis and keratoconjunctivitis, blepharitis and blepharoconjunctivitis. |
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| Despite hypersensitivity reactions polysporin is generally considered to be gentle on the cornea. |
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| Contraindications | Hypersensitivity to any of its components. | |
| Pediatric use | Safety and effectiveness in children not established. | |
| Pregnancy | Category C | |
| Bacitracin primarily active against gram positive bacteria. Polymyxin B primarily active against gram negative bacteria. |
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