Ocuflox  (U.S.N.L.M.)
Dosing/ Corneal Ulcer 1 or 2drops q30min 1st day, then awaken after 4hr sleep and then
after another 6 hr then qhr for 2 days then qid to end of treatment
1 or 2drops q30min 1st day, then awaken after 4hr sleep and then after another 6 hr then qhr for 2 days then qid to end of treatment
Dosing/ Conjunctivitis 1 or 2 drops q2-4hr x 2days, qid next 5 days
Chem Specs ofloxacin 0.3%
Quantities 5, 10ml
Cost 51.28/5ml
Class fluoroquinolone, second generation
Action Bactericidal via inhibition of DNA gyrase.
Activity Broad spectrum, effective against Pseudomonas aeruginosa
poor choice for chlamydia and mycoplasma.
Usage Indicated for the treatment of corneal ulcers and conjunctivitis.
Excellent corneal penetration. Second-generation fluoroquinolone antibiotics
were good topical agents due to wide spectrum of antimicrobial activity, low toxicity,
high potency, prolonged tear film concentration, and stability in solution.
Excellent corneal penetration. Second-generation fluoroquinolone antibiotics were good topical agents due to wide spectrum of antimicrobial activity, low toxicity, high potency, prolonged tear film concentration, and stability in solution.
Contraindications Quinolone hypersensitivity
Pediatric use Over 1 year
Pregnancy No adequate and well-controlled studies in pregnant women. Embryocidal
in rats and in rabbits when given 9000 times the maximum daily ophthalmic dose
No adequate and well-controlled studies in pregnant women. Embryocidal in rats and in rabbits when given 9000 times the maximum daily ophthalmic dose
0.005% BAK preserved.
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