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          Natacyn  (U.S.N.L.M.)
| ||
|---|---|---|
| Dosing/ keratitis | 1 drop q1-2 hr x 3-4 days, then 1 drop 6-8 times/day. Continue 14 to 21 days. For blepharitis and conjunctivitis reduce initial dose to 4 to 6 drops per day. |
|
| Chem Specs | natamycin 5% | |
| Quantities | 15ml glass bottle with dropper | |
| Cost | 110.00 | |
| Class | Polyene amphoteric macrolide antifungal | |
| Action | Alters fungal cell membrane permeability by binding with membrane sterols. | |
| Activity | Active against a variety of yeast and filamentous fungi including Candida, Aspergillus, Cephalosporium, and Fusarium. |
|
| Usage | Indicated for the treatment of fungal blepharitis, conjunctivitis, and keratitis caused by susceptible organisms including Fusarium solani keratitis. |
|
| Alternatives include amphotericin B 0.15% and flucytosine 1% 150 mg/kg. | ||
| Contraindications | Hypersensitivity to natamycin any Natacyn components. | |
| Pediatric use | Safety and effectiveness in pediatric patients have not been established. | |
| Pregnancy | Category C | |