Moxeza  (U.S.N.L.M.)
Dosing/ conjunctivitis 1 drop bid for 7 days
Dosing/ corneal ulcer In office loading dose then 2drops q15min for 2-3hr, then qhr,
q3-4hr overnight (ung hs less severe cases), qhr day 2, then
q2hr to significant resolution, then qid to day 14.
In office loading dose then 2drops q15min for 2-3hr, then qhr, q3-4hr overnight (ung hs less severe cases), qhr day 2, then q2hr to significant resolution, then qid to day 14.
Chem Specs moxifloxacin 0.5%
Quantities 3 ml in 4ml bottle
Cost 184.00
Class fourth-generation fluoroquinolone
Action Bactericidal via inhibition of DNA gyrase.
Activity Active against a broad range of gram negative and positive
organisms. Click heading for details in package insert.
Active against a broad range of gram negative and positive organisms. Click heading for details in package insert.
Usage Indicated for bacterial conjunctivitis, off label for corneal ulcer.
Enhanced gram positive activity with side chains which combat resistance and enhance
potency. Superior time-kill characteristics. Better solubility in ophthalmic solution allows
higher concentration. Biphasic molecule may explain enhanced corneal penetration.
Enhanced gram positive activity with side chains which combat resistance and enhance potency. Superior time-kill characteristics. Better solubility in ophthalmic solution allows higher concentration. Biphasic molecule may explain enhanced corneal penetration.
Contraindications Hypersensitivity to Moxifloxacin, other quinolones or any components.
Pediatric use Safety and effectivenessin infants below 4 months of age have not been established.
Pregnancy Category C
Self preserved. bid dosing vs. tid dosing of Vigamox.
Xanthan gum increases time of residence on the eye.
    N.L.M. DailyMed page for Moxeza         PDR page for Moxeza