Lotemax   (U.S.N.L.M.)
Dosing 1 or 2 drops qid,   up to 1 drop qh in 1st week if needed.
Chem Specs loteprednol etabonate 0.5%
Quantities 2.5ml, 5ml, 10ml, 15ml
Cost 205.00/5ml
Class Ester based "soft" steroid suspension
Action Anti-inflammatory
Usage Indicated for the treatment of allergic conjunctivitis, acne rosacea, superficial
punctate keratitis, herpes zoster keratitis, iritis, cyclitis, post surgical inflammation and
other steroid responsive inflammations of the anterior segment and adnexia.
Used off label as brief adjunctive dry eye treatment. Sometimes as front load to
Restasis treatment. Used off label to reduce inflammatory sequelae of EKC.
Contraindications Most viral diseases of the cornea and conjunctiva including epithelial herpes simplex
keratitis, vaccinia, and varicella, mycobacterial and fungal disease. Hypersensitivity
to any of the ingredients of this preparation and to other corticosteroids.
Pediatric use Safety and effectiveness in pediatric patients have not been established.
Pregnancy Embryotoxic and teratogenic in rabbits at 35 times the maximum daily clinical dose but not at 6x.
Fungal and bacterial overgrowth, cataract formation, globe perforation possible with long term use.
BAK preserved. Alrex is the 0.2% preparation of loteprednol etabonate.
From the package insert: "As with all ophthalmic preparations containing benzalkonium
chloride, patients should be advised not to wear soft contact lenses when using LOTEMAX."
    N.L.M. DailyMed page for Lotemax          PDR page for Lotemax