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Iopidine (U.S.N.L.M.)
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| Dosing | 1 or 2 drops tid | |
| Chem Specs | apraclonidine 0.5%, (1% singles) | |
| Quantities | 5, 10ml, 0.1mL singles (2 per pouch) | |
| Cost | 80.00/5ml | |
| Class | alpha agonist | |
| Action | Reduces aqueous production and increases uveoscleral outflow. | |
| Usage | Indicated for short-term adjunctive therapy in patients on maximally tolerated medical therapy who require additional IOP reduction. |
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| Tachyphylaxis is common, so short-term use is recommended. | ||
| Contraindications | Monoamine oxidase (MAO) inhibitor usage, severe cardiovascular disease, low blood pressure, or bradycardia. Hypersensitivity to apraclonidine, clonidine, or components. |
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| Pediatric use | Safety and effectiveness in pediatric patients have not been established. | |
| Pregnancy | Category C | |
| 1% singles intended for pre and post surgical treatment. | ||
| Side-effects may include eyelid retraction, mydriasis, conjunctival blanching, dry mouth, headache, fatigue, lethargy and allergy (20 to 30%). BAK preserved. |
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