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Durezol emulsion (U.S.N.L.M.)
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|---|---|
| Dosing (post surgical) | 1 drop qid for 2 weeks beginning 24 hrs after surgery. Then bid for 1 week. Then taper. |
| Dosing (anterior uveitis) | 1 drop q2hr to qid depending on severity for first 24 to 48 hr. Then reduce by half for 1 week. Continue to taper. |
| Chem Specs | difluprednate 0.05% |
| Quantities | 5ml |
| Cost | 118.00 |
| Class | (difluorinated) corticosteroid. |
| Action | Anti-inflammatory |
| Usage | Indicated for the treatment of inflammation and pain associated with ocular surgery. |
| Durezol with qid dosing found to be comparable to Pred Forte with 8x/day dosing for anterior uveitis. Suited for the more severe ocular inflammations. |
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| Contraindications | Most viral diseases of the cornea and conjunctiva including epithelial herpes simplex keratitis, vaccinia, and varicella, mycobacterial and fungal disease. Hypersensitivity to any of the ingredients of this preparation and to other corticosteroids. |
| Pediatric use | Safety and effectiveness in pediatric patients have not been established. |
| Pregnancy | Category C |
| Fungal and bacterial overgrowth, cataract formation, elevated intraocular pressure, globe perforation possible with long term use. |
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| Excellent tissue penetration. Possible enhanced dose uniformity when compared to acetate suspensions. |