Brim-Dorâ„¢ PF  (U.S.N.L.M.)
Dosing b.i.d.
Chem Specs brimonidine 0.15%,   dorzolamide 2.0%
Quantities 10ml,
Cost 108.00
Class     brimonidine:   Relatively selective alpha-2 agonist.
    dorzolamide:   Carbonic anhydrase inhibitor
Usage Preservative-free, single container preparation can reduce surface toxicity and
enhance compliance. Requires refrigeration.
Contraindications
brimonidine

neonates and infants (under the age of 2 years)

dorzolamide

Sulfonamide hypersensitivity.
Pediatric use Safety and effectiveness in pediatric patients have not been established.
Pregnancy Category C. Animal teratogenicity at 37 times the normal human ophthalmic dose.
Bottle with one way valve requires Refrigeration.
Individual drugs are FDA approved but the combination is not.