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Azopt (U.S.N.L.M.)
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| Dosing | 1 drop tid | |
| Chem Specs | brinzolamide 1% | |
| Quantities | 2.5, 5, 10, 15ml | |
| Cost | 82.00/5ml | |
| Class | carbonic anhydrase inhibitor | |
| Action | Inhibition of carbonic anhydrase II in the ciliary processes presumably slows the formation of bicarbonate with subsequent reduction in sodium and fluid transport. |
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| Usage | Indicated for elevated IOP of ocular hypertension or open-angle glaucoma. | |
| Azopt is a sulfonamide and is absorbed systemically. Fatalities, Stevens-Johnson syndrome, toxic epidermal necrolysis, fulminant hepatic necrosis, agranulocytosis, aplastic anemia, and other blood dyscrasias have occurred. |
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| Contraindications | Hypersensitivity to sulfonamides or any other product contents. | |
| Pediatric use | Safety and effectiveness in pediatric patients have not been established. | |
| Pregnancy | Category C | |
| Less sting than dorzolamide 2%. May be used concomitantly with other IOP lowering topicals. BAK preserved. |
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