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Alphagan-P(U.S.N.L.M.)
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| Dosing | 0.1% or 0.15% tid 8hrs apart | |
| Chem Specs | brimonidine 0.1%, 0.15% | |
| Quantities | 5, 10, 15ml | |
| Cost | 50.00/5ml | |
| Class | Relatively selective alpha-2 adrenergic receptor agonist. Clonidine derivative. |
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| Action | Reduces aqueous production and increases uveoscleral outflow. Peak ocular hypotensive effect occurres at 2 hours post-dosing. |
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| Activity | Stimulates alpha 2 receptors in the non-pigmented ciliary epithelium. | |
| Usage | Indicated for the lowering of intraocular pressure in patients with open-angle glaucoma or ocular hypertension. |
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| Additive IOP reduction with beta-blockers and carbonic anhydrase inhibitors. Caution with severe cardiovascular disease, depression, and cerebral or coronary insufficiency. |
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| Contraindications | Hypersensitivity to brimonidine or any of its components and those taking MAO inhibitors. |
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| Pediatric use | > 2 years | |
| Pregnancy | Category B | |
| "P" signifies Purite® preservative. 0.2% Brimonidine with BAK is available from B&L (check literature for side effects of 0.2% with BAK.) 0.2% Bimonidine causes miosis with a similar time course and fewer side effects than dapiprazole 0.25% and has been suggested for dilation reversal. |
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